Friday, March 6, 2009

Oster Imperial Blender

Streichholzbeinchen (SLS)

In American Dendroboard I found several articles on SLS (spindly leg syndrome) and traced (http://www.thebdg.org/library/illnesses/spindleleg1.htm, Developments in the Study of spindle leg syndrome 1-3) It involves the training of Streichholzbeinchen with the known phenomena. forelimb thin, which is not very flexible, low education and a stiffening of the muscles in the elbow joint. In the Histology refers to a partial atrophy of the spinal cord and the medulla (medulla oblongata) is not closed. In SLS can be found not only stunted forelimbs, there is evidence of profound deformity. The hypothesis is that a genetic defect prevented in a very early stage, the correct formation of the anterior limb.

is the key sentence: "The German investigators were able to generate this (SLS) in the laboratory, and each time they introduced a disrupter, the frogs developed spindly legs. The examiner was Dr Th Wöhrmann, then University of Aachen. Unfortunately, so far I could not obtain the primary literature.

It is a disorder of the expression of the gene XLHBox 1 of the Homeobox. The homeobox is a fraction of the genome that is active in the early development and encodes transcription factors that activate a variety of other genes and induce fundamental developments, such as the formation of the anterior limb. The disruption of the reading can be done by a variety of influences and is either already in frogs or in the early stages of the eggs. The animal experimental effort to identify likely full range of possible noise on the reading of the gene would be disproportionate and would likely be on the Result result, the food and the attitude were to improve substantially.